Data Science and Machine Learning are two interconnected fields that play a pivotal role in modern technological advancements. Data science involves extracting insights and knowledge from vast amounts of data using various tools and techniques. This includes data collection, cleaning, analysis, and interpretation to uncover valuable patterns and trends. On the other hand, machine learning is a subset of artificial intelligence (AI) that focuses on developing algorithms and models capable of learning from data to make predictions and decisions. Machine learning algorithms can automatically improve their performance over time by learning from new data, making them crucial for tasks such as image recognition, natural language processing, and predictive analytics. Together, data science and machine learning empower businesses and researchers to leverage data-driven insights for informed decision-making and innovation across diverse domains. This book is intended for the first course in Data Science and Machine Learning and covers the required topics in sufficient depth to meet the requirements of the readers.