Developmental Genetics
Developmental Genetics

Tags: Developmental Genetics, Life Sciences, Genetics/Molecular/Cellular Biology, Gurbachan S. Miglani

Developmental Genetics

Development is behind what one looks like. It is directed by genes, the units of heredity, which are made up to deoxyribonucleic acid (DNA) in all animals (including man), plants, microorganisms and most of the viruses except in some viruses where ribonucleic acid (RNA) is the genetic material. Developmental Genetics integrates the two disciplines of development and genetics into one. Key Features:  Each chapter begins with a brief introduction and historical background. The text explains both classical and recent material.  Various phenomena of developmental genetics explained with examples of animals, plant, bacteria and viruses.  Text explained with suitable examples, illustrations, tables and figures. List of references and review questions given at the end of each chapter  Exhaustive glossary, author index and subject index given at the end of the book. This book is essential reading for postgraduate in developmental genetics, teachers teaching this subject and developmental biologists conducting research in this area. It is also suitable for candidates preparing for ARS/UGC NET examination.

1. Introduction: Preformation versus Epigenesis *Ontogeny, Phylogeny and Recapitulation
   *Mosaic and Regulation Eggs *Genetics *Development *Developmental Genetics *Steps
    in  Development *Role of Genes in Development *Understanding Development in
   Genetics Terms
2. Inheritance of Developmental Difference: Early Ideas about Heredity *Continuity of Life
    *Qualitative and Quantitative Traits *Genotype and Environmental Variation Mendelian
     Principles *Concepts of Dominance *Heterosis and Hybrid Vigor *Reverse Genetics in
     Mendel's Wrinkled Character *Molecular basis of Mendelian Genetics *Mendelism-An
     Exception or Rule *Mendels Results and Linkage *Chromosome Theory of Inheritance
    *Sex-Linked, Sex-Limited and Sex-Influenced Inheritance *Multiple Allelism  *Gene-Gene
     Interactions *Tiem of Segregation *Endosperm Genetics *Mutations *Quantitative Traits
    *Penetrance and Expressivity *Pleiotropy *Phenocopies *Homestasis
3. Genome Constancy in Development: Totipotency *Exceptions in Genome Constancy
4. Nucleus and Nucleo-Cytoplasmic Interactions: Nucleus *Nucleo-cytoplasm Interactions
5. Gene-Protein-Phenotype Relationship: Chemical Nature of the Genetic Material *Molecular Structure of DNA *Molecular Structure of RNA *Properties of Genetic Material *DNA Replication *Biological Function of the Gene *Gene Expression *Analysis of Gene Expression *Environmental and Gene Expression *Types of Transcripts *Genetic Code *Protein Biosynthesis *Protein Targeting *Protein Secretion *Molecular Chaperone *Protein Turnover *Protein Degradation *Protein-Phenotype System
6. Gene Regulation and Differentiation: Gene regulation in Prokaryotes *Gene regulation in Lambda Phage *Gene regulation in Eukaryotes *Messenger RNA and Differentiation *Circadian Clock
7. Cells Development: Cell Cycle *Cell Proliferation *Cell Division Axis *Cell Elongation *Cell Determination and Differentiation *Transdetermination *Pattern Formation in Polytene Puffs *Trans differentiation *Cell Polarity *Cellular Homeostasis *Regulation of Diverse Cellular Activities *Cell and Tissue Regeneration *Cell Adhesion *Cell Commitment *Cell Migration *Cell Motility *Cellular Responses *Cell Competition *Intercellular Junctions *Cell-Cell Interaction *Cytoskelton
8. Cell-Specific Gene Activation and Tissue Differentiation: Origin of Different Cell Types *Cell-Specific Gene Activation *Specificity in Eukaryotic Transcription *Tissue Differentiation 9. Plant Embryology: Meiosis *Fertilization in Angiosperms *Endosperm Development *Embryo Formation *Storage Proteins
10. Gamete Formation, Fertilization and Cleavage in Animals: Primordial Germ Cells *Spermatogenesis *Oogenesis *Fertilization *Cleavage
11. Animal Development: Drosophila *Sea Urchin *Mammals *Frog *Caenorhabditis Elegans *Zebrafish *Blastogenesis *Bone Marrow Stem Cells
12. Dosage Compensation and Sex Determination: Dosage compensation *Mechanisms of Dosage Compensation *Sex Determination *Noncoding DNA Hypothesis for Sex-Determination *Evolutionary Relationships Among Sex-Determining Mechanisms *Sex Differentiation *Events in Sex Determination
13. Ageing and Apoptosis: Agening *Theories of Ageing *Genetics of Ageing *Postponement of Ageing *Apoptosis *Reaper Model *Regulators of Apoptosis *Miotchondrial Pathways of Apoptosis *Role Morphogens in Apoptosis *Programmed Cell Death in Plants
14. Pattern Formation and Epigenetics: Pattern Formation *Positional Information and Developmental Patterns *Epigenetics *DNA Methylation and Epigenetics *Epigenetic Reprogramming *Linking Conventional Genetics with Development *Epigenetic Code
15. Morphogenesis: Morphogens *Morphogenesis in Viruses *Morphogenesis in Bacillus Subtilis *Morphogenesis in Slime Mold *Morphogenesis in Green Algae *Morphogenesis in Animals *Binary Switch Genes *Process of Morphogenesis *Organ Development *Plant Morphogenesis 16. Homeosis: Drosophila Homeosis *Silkworm Homeosis *Tribolium Homeosis *Mode of Action of Specification *Common Coding.



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